Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PYGB All Species: 31.82
Human Site: S314 Identified Species: 63.64
UniProt: P11216 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P11216 NP_002853.2 843 96696 S314 D I I R R F K S S K F G C R D
Chimpanzee Pan troglodytes XP_525293 1007 114448 S478 D I I R R F K S S K F G C R D
Rhesus Macaque Macaca mulatta XP_001100555 843 96591 S314 D I I R R F K S S K F G C R D
Dog Lupus familis XP_534201 809 92651 D287 S S K F G C R D P V R T C F E
Cat Felis silvestris
Mouse Mus musculus Q8CI94 843 96711 S314 D I I R R F K S S R F G C R D
Rat Rattus norvegicus P53534 838 96156 S314 D I I R R F K S S K F G C R D
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001026205 843 96712 S314 D I I R R F K S S K F G C Q D
Frog Xenopus laevis NP_001080170 843 96849 S314 D I I R R F K S S K F G C R D
Zebra Danio Brachydanio rerio NP_997974 843 97409 S314 D I I R R F K S S K F G C R D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9XTL9 844 96978 A314 D I I R R Y K A S K F G S R E
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SD76 841 95141 E318 D I I S R F H E R S T T E G S
Baker's Yeast Sacchar. cerevisiae P06738 902 103525 K372 D I L R R F K K S K R P W T E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 83.7 99.1 90.9 N.A. 95.6 94.9 N.A. N.A. 90.9 87.6 86.8 N.A. 72 N.A. N.A. N.A.
Protein Similarity: 100 83.7 99.6 94.1 N.A. 98.5 97.6 N.A. N.A. 97 95.9 95.1 N.A. 86.7 N.A. N.A. N.A.
P-Site Identity: 100 100 100 6.6 N.A. 93.3 100 N.A. N.A. 93.3 100 100 N.A. 73.3 N.A. N.A. N.A.
P-Site Similarity: 100 100 100 20 N.A. 100 100 N.A. N.A. 100 100 100 N.A. 93.3 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 45.9 48.1 N.A.
Protein Similarity: N.A. N.A. N.A. 62.2 64.4 N.A.
P-Site Identity: N.A. N.A. N.A. 33.3 53.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 33.3 66.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 9 0 0 0 0 0 0 75 0 0 % C
% Asp: 92 0 0 0 0 0 0 9 0 0 0 0 0 0 67 % D
% Glu: 0 0 0 0 0 0 0 9 0 0 0 0 9 0 25 % E
% Phe: 0 0 0 9 0 84 0 0 0 0 75 0 0 9 0 % F
% Gly: 0 0 0 0 9 0 0 0 0 0 0 75 0 9 0 % G
% His: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % H
% Ile: 0 92 84 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 9 0 0 0 84 9 0 75 0 0 0 0 0 % K
% Leu: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 9 0 0 9 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % Q
% Arg: 0 0 0 84 92 0 9 0 9 9 17 0 0 67 0 % R
% Ser: 9 9 0 9 0 0 0 67 84 9 0 0 9 0 9 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 9 17 0 9 0 % T
% Val: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % W
% Tyr: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _